Mass General Brigham has reported promising early findings on the use of ultra-low field (ULF) MRI for breast imaging, suggesting it could become a more affordable and accessible option for screening in the future. The study, published in Scientific Reports, highlights the technical feasibility of this emerging technology.
The research team demonstrated that ULF MRI can capture key structural details of the breast. According to lead investigator Matthew Rosen, PhD, the results represent an encouraging proof of concept, though larger studies are necessary to confirm diagnostic accuracy. He emphasized the team’s goal of developing safer, more comfortable, and lower-cost screening methods to expand patient access.
Current U.S. guidelines recommend mammography for women aged 40 to 74. Unlike mammography, ULF MRI does not require breast compression, which many patients find uncomfortable. It also avoids exposure to ionizing radiation. Although conventional MRI is sometimes used for high-risk patients, it is not part of routine screening due to high costs and limited availability. In contrast, ULF MRI systems are estimated to cost less than five percent of standard MRI machines and have lower long-term operating expenses.
In the pilot study, 14 participants underwent ULF MRI scans, including women with no history of breast cancer, individuals previously diagnosed with breast cancer, and one participant with a benign mass. Three radiologists reviewing the scans were able to identify essential breast structures and differentiate fibroglandular from fatty tissue. Some interpretation differences were attributed to the novelty of the technology and may improve with experience.
Researchers conclude that while ULF MRI shows promise, further refinement and larger clinical trials are needed to determine its diagnostic accuracy and ensure it meets established clinical imaging standards
